How long can platelets be safely stored before they expire?

Platelets can be safely stored for up to 5 days before they expire. This storage duration is critical for maintaining the viability and effectiveness of platelets for transfusion. During this time, platelets are kept at room temperature under continuous agitation, which helps preserve their functionality.

The 5-day storage limit is primarily due to the biological and metabolic changes that occur in platelets over time. After 5 days, the risk of bacterial contamination and the decrease in platelet functionality increases significantly, which could compromise patient safety if transfused. While some blood components can be stored for longer periods, platelets have a much shorter shelf life due to their unique properties and the requirements for maintaining their effectiveness in treating conditions like thrombocytopenia. This understanding is vital for healthcare professionals involved in blood transfusion practices to ensure optimal patient outcomes.