How are allergic reactions to blood transfusions typically managed?

Allergic reactions to blood transfusions are typically managed by administering antihistamines and closely monitoring the patient. This approach is effective because antihistamines help counteract the histamine release that occurs during an allergic reaction, alleviating symptoms such as itching, hives, or mild respiratory issues. Monitoring the patient is critical to ensure that the reaction does not escalate to a more severe form, such as anaphylaxis.

While stopping the transfusion entirely might seem like a reasonable response to an allergic reaction, this is usually one of the first steps taken to prevent further exposure to the allergen. However, in cases of mild allergic reactions to transfusions, continuing with antihistamine administration while monitoring can allow the transfusion to either continue safely or be resumed after symptom resolution. The use of antibiotics is not relevant for allergic reactions, as they are specific to treating infections rather than immune responses. Increasing the transfusion rate is contraindicated as it may worsen the reaction. Thus, managing allergic responses effectively with antihistamines and monitoring provides a safe, supportive treatment strategy in a clinical setting.